Intestinal bacteria may help determine whether we are lean or obese. New evidence indicates that gut bacteria alter the way we store fat, how we balance levels of glucose in the blood, and how we respond to hormones that make us feel hungry or full. How modern life screws up our gut and makes us fat and diabetic. What all of this research suggests is that healthy gut bacteria is crucial to maintaining normal weight and metabolism. Recent evidence suggests that the gut microbiota play a role in energy harvest, storage, and expenditure. The gut microbiota may also influence the development of conditions characterized by low-level inflammation, such as obesity and type 2 diabetes, through systemic exposure to bacterial lipopolysaccharide derived from the intestinal microbiota. This review will examine the role of the gut microbiota in energy harvest and fat storage, explore differences in the microbiota in obese and lean individuals, and evaluate potential mechanisms for modulating the gut microbiota to influence metabolic parameters in humans.
Bacteria in your gut may be the secret to a sexy stomach. Let’s consider how we’ve disrupted our gut flora, and the strength of evidence showing how we’ve transformed our once-thriving inner ecosystem into a polluted pond of fat-favoring microbes. Can’t seem to lose fat and keep it off? Have crazy cravings? It could be caused by a problem with your natural gut bacteria. Here’s why and how you can fix it.
If you didn’t already know, in the late 1970s, this country adopted a near universal fear of dietary fat, and ironically, it might be what’s behind the current obesity epidemic. An excess of bacteria in the gut can change the way the liver processes fat and could lead to the development of metabolic syndrome, according to health researchers. Mice fed a diet high in saturated fat show shifts in their gut microbes and develop obesity-related inflammation.
How Your Gut Bacteria Can Boost Your Weight Loss
Obesity has long been blamed on laziness and lack of will power, but exciting new research shows the composition of your gut bacteria, which may have been set since birth, can play a deciding role in whether you’re thin or fat. 2) gut microbiota on a high-fat diet may convert dietary choline into hepatotoxic methylamines, reducing choline bioavailability of choline, which is necessary for the assembly and secretion of VLDLs and eventually promoting hepatic steatosis, IR, and lipoperoxidation (6). Recent work has shown that gut bacteria can initiate the inflammatory state of obesity and IR through the activity of lipopolysaccharide (LPS), a component of the gram-negative bacterial cell walls, which can trigger the inflammatory process by binding to the CD14 toll-like receptor-4 (TLR-4) complex at the surface of innate immune cells. Gut bacteria are totally dependent on what we eat for survival. If we eat a diet loaded with meat, fats and sugars, with little fiber, certain types of bacteria will take over and survive. Call it a hidden ally: The right germs just might be able to help fight fat. Different kinds of bacteria that live inside the gut can help spur obesity or protect against it, say scientists at Washington University in St. More MoJo coverage of bacteria and health:. We all carry a few pounds’ worth of microbes in our gut, a complex ecosystem collectively called the microbiota. Scientists do. A paper published today in the journal Cell Reports suggests that one secret to the bears’ success may lie in their gut bacteria. Researchers identified 34 different gut bacteria that may play a role in body fat and good cholesterol, affecting overall heart health. Did you know that your gut is interacting with bacteria every day to do more than help you digest food? The gut is so unique to every individual that scientists are only recently becoming more aware of the existence of a complex network of nerves that line our stomach and gut and is referred to as the second brain. High fat, low fiber diets are known triggers of inflammation and can increase the permeability of the intestines (3). Gut microbes from lean people helped prevent mice from becoming obese but only if the animals ate a healthy diet. On the high-fat diet, the lean mice’s bacteria weren’t able to colonize the obese mice, and the mice developed obesity.